Low Doses facts

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LSD is non-addictive, is not known to cause brain damage, has extremely low toxicity relative to dose, there have been no documented deaths from an overdose, it is physiologically well tolerated and there is no evidence for long-lasting physiological effects on the brain or other organs.

how are enzymes effective at low concentrations?

Dolphins get high off puffer fish by holding the fish in their mouths and passing it around between them, causing the fish to release defense toxins which are euphoric in low doses. After they get high, they let the puffer fish go.

Bpa at low doses acts like which hormone?

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why are new drugs given at low doses at first?

1. The common practice to produce antivenom comes from horses. They are given very low doses of snake venom over long periods of time. Eventually the blood is taken from the animal, and the antibodies are purified out. The antibodies inside that blood then bind and neutralise the venom.

2. In low, pharmaceutical-grade doses, methamphetamine may actually repair and protect the brain in certain circumstances. Some preliminary research suggests that meth can be neuroprotective against stroke and traumatic brain injury, even stimulating the growth of brain cells.

3. The median lethal dose (LD50) of marijuana is estimated (at the low end) at 1:20,000. This means a person would have to smoke around 15,000 pounds of marijuana in about 15 minutes to die from it.

4. 30-40 minutes after eating a dose of sugar or starch, the body creates a low blood sugar level (hypoglycemia) where brain function is greatly reduced

5. Apple seeds contain low doses of toxin called cyanide. Luckily, accidental ingestion of few seeds does not induce negative effects. One cup of seeds results in toxicity that may end up fatally.

6. Photographs of individuals who had consumed a low dose of alcohol were rated as more attractive than photographs of sober individuals.

7. A 2002 study published in the Proceedings of the National Academy of Sciences showed that exposure to a herbicide at low ecologically relevant doses induces male frogs to become hermaphrodite and demasculinized

8. Birds surrounding Chernobyl have smaller brains than normal - Low dose radiation can have significant effects on normal brain development as reflected by brain size and therefore potentially cognitive ability

9. Hormesis, the biological phenomenon whereby a beneficial effect (improved health, stress tolerance, growth or longevity) results from exposure to low doses of an agent that is otherwise toxic or lethal when given at higher doses.

10. Farmed chickens in India are dosed with strongest antibiotics in the world in order to keep the price of meat low.

Why are low doses given in clinical trials?

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When exposed to low doses of LSD, spiders' webs were "even better proportioned and more exactly built than normally."

Low-dose aspirin does not reduce the risk of cardiovascular death in older patients; even among those with elevated risk factors. (JAMA) - source

Methamphetamine is neuroprotective in low doses while neurotoxic in high doses - source

Low doses of ionizing radiation can be beneficial rather than detrimental to us, stimulating the activation of cellular repair mechanisms that protect against disease - a phenomenon known as Radiation Hormesis.

There is a scientific theory called Radiation Homeostasis, which hypothesizes that low doses of ionizing radiation is beneficial to health by stimulating the activation of repair mechanisms that protect against disease - source

Safety of low doses of quetiapine when used for insomnia?

When exposed to low doses of LCD, spiders' webs were "even better proportioned and more exactly built than normally."

Obesity in the United States may be driven from exposure to low-dose antibiotics

The FDA allows a 15% variation between generic and name brand meds which can play a role in why women get pregnant while on birth control pills since they are also becoming increasingly low dose.