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Sickle Cell facts

While investigating facts about Sickle Cell Anemia and Sickle Cell Disease, I found out little known, but curios details like:

In 1984 an 8 year old girl with sickle cell disease developed acute myeloid leukemia. To treat the cancer, the doctors gave her chemo and a stem cell transplant from her sibling. Not only did this cure her cancer, but it cured her SCD too. She remains disease free nearly three decades later.

how sickle cell anemia is inherited?

The alien in Alien was played by a Nigerian man named Bolaji Badejo. He died of sickle cell anemia in 1992, at the age of 39.

What's sickle cell anemia?

In my opinion, it is useful to put together a list of the most interesting details from trusted sources that I've come across answering what's sickle cell disease. Here are 34 of the best facts about Sickle Cell Trait and Sickle Cell Crisis I managed to collect.

what's sickle cell?

  1. Sickle-cell anemia protects the carrier from malaria, which is why it is seen mostly in people of African descent

  2. A man turned himself in after beating his then 23 year old girlfriend to death. After the autopsy, it was determined that she died of natural causes (Sickle Cell), and she would've died the next day regardless. He pled Guilty to Assault and Battery.

  3. Sickle Cell Anemia (a condition which disproportionately afflicts Africans) provides protection against Malaria. It is believed that the reason why Africans are more likely to have S.C.A. is Africans benefited from the condition from living in a Malaria risk location.

  4. Between 1990 and 1992 Mae served on the World Sickle Cell Foundation Board of Directors.

  5. Saudi Arabia promotes practice of marriage between close relatives which has produced high level of several genetic disorder including thalassemia, sickle cell anemia, spinal muscular atrophy, deafness and muteness.

  6. Sickle cell anemia provides resistance to malaria, and is far more prevalent in areas affected by malaria.

  7. People with Sickle Cell Trait are 90% more secure towards severe Malaria conditions, thus their number continues to rise in West Africa. Child of two parents suffering Sickle Cell Trait is able to inherit Sickle Cell Desease which implies an increased risk of death and severe pain attacks.

  8. African-Americans and Hispanics are required to take a blood test for sickle cell before getting a marriage licence in the State of New York.

  9. Heterozygous carriers of Sickle-Cell Disease experience only mild effects from the disease and are extremely resistant to malaria, making it a sought after gene in some parts of the world

sickle cell facts
What sickle cell patients should avoid?

Why sickle cell anemia is resistant to malaria?

You can easily fact check why sickle cell anemia is common in africa by examining the linked well-known sources.

Linus Pauling-adored scientist of renown and winner of two Nobel prizes-suggested that carriers of sickle cell genes should have tattoos on their foreheads to discourage fellow carriers from mating with them. - source

In 1949 he and his colleagues published 'sickle Cell Anemia, a Molecular Disease" which was the first proof that an abnormal protein could cause a disease.

The rapper Prodigy from Mobb Deep suffered from sickle-cell anemia and passed away when accidentily choking on an egg while hospitalized for his condition

Individuals more likely to become very ill from the flu include those with asthma, diabetes, heart disease, liver disease, kidney disease, lung disease, sickle cell disease, neurological diseases that affect breathing or the throat's ability to swallow, pregnant women, children under the age of 5 (under 2 especially). Adults over 50, and those with weakened immune systems from diseases such as HIV.

When sickle cell anemia is diagnosed?

She is a member of the American Medical Association, the American Chemical Society and from 1990 to 1992 served on the board of directors of the World Sickle Cell Foundation.

How sickle cell disease is inherited?

Sickle cell anemia confers resistance to malaria to carriers.

28% of newborns were tested for Sickle-Cell anemia in France in 2007. This form of anemia is not found in Europeans of French origin, but exclusively people of African, near Eastern, and Indian origin.

Bolaji Badejo, the Nigerian born artist who played the Alien in Ridley Scott's Alien, was cast as the Alien after being randomly observed in a bar as an "impossibly tall and skinny" man; beloved by all he knew, he died In December 1992 from complications of sickle-cell anemia in Nigeria

9/10 men with sickle cell anaemia will suffer a medical emergency called priapism- a sustained and painful erection lasting several hours.

When sickle cell anemia was discovered?

The entire illness of sickle cell anemia is caused by an error in a single nucleotide. The error causes the glutamic acid codon in the b-globin gene to become valine instead and creates a defective protein in all of one’s blood cells as a result.

Malaria-prone regions generally have significantly higher rates of sickle cell anaemia, as carriers for the recessive anaemia gene have a natural genetic resistance to malaria

Sickle-cell disease may have evolved as protection against Malaria

Sickle cell anemia is an example of natural selection in humans. Regions of the globe with higher rates of sickle cell are those with higher rates of malaria, as malaria is not effective against sickle cells. Being a carrier (one normal + one sickle gene) made one fit in that environment.

Tupac died on september 13, 19 days after prodigy spitted "clocks tick your days are numbered in low digits" on the infamous disstrack Drop a gem on em, being mad about pac mocking his sickle cell disease in Hit em up when there wasn't any prior beef whatsoever.

How sickle cell anemia is caused?

Sickle Cell Trait protects against Malaria

People with sickle-cell anemia are genetically immune to malaria.

Sickle Cell Disease is sort of the bodies way of fighting Malaria

One Child’s Sickle Cell Mutation Helped Protect the World From Malaria

People with sickle cell trait are protected against malaria

Oak Park and River Forrest High school, a school in Illinois that has produced some of the best minds in a bunch of different fields. Notable alum include Ernest Hemingway, the scientists who discovered Sickle Cell Anemia, Global Warming, and stem cells, as well as the founder of McDonalds.

This is our collection of basic interesting facts about Sickle Cell. The fact lists are intended for research in school, for college students or just to feed your brain with new realities. Possible use cases are in quizzes, differences, riddles, homework facts legend, cover facts, and many more. Whatever your case, learn the truth of the matter why is Sickle Cell so important!

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